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Testicular Cancer

Home / Men's Health Conditions / Testicular Cancer

What is testicular cancer?

Testicular cancer is a type of cancer that develops in the tissues of one or both testicles. If found early, testicular cancer can be cured.

There are two main types of testicular cancer:

  • germ cell tumours – occurring in the cells that make sperm within the testicles
  • stromal cell tumours – occurring in the supportive tissue of the testicles.

Germ cell tumours are the most common types of testicular cancer, and there are two main types of these:

  • seminomas – slowly-growing cancers that mostly occur in people aged 25 to 45
  • non-seminomas – cancers that occur in people who are in their late teens or early 20s.

How common is testicular cancer? 

The Cancer Council estimates that more than ‘1,000 people were diagnosed with testicular cancer in 2023. The average age at diagnosis is 36 years old.’

What causes testicular cancer?

Specific causes of testicular cancer are unknown, but some of the known risk factors include:

  • having an immediate blood relative with testicular cancer
  • a history of testicular cancer in one testicle, making it more likely to develop in the other testicle
  • infertility
  • having an undescended testicle as an infant.

Testicular injuries, hot baths and tight clothes do not cause testicular cancer.

Testicular Cancer image

What are the symptoms of testicular cancer?

The most common symptoms of testicular cancer are:

  • a lump in one or both testicles
  • swelling in one or both testicles
  • a change in the size or shape of one or both testicles.

In the early stages of the condition, you may notice no symptoms at all.

Some of the less common symptoms of testicular cancer may include:

  • heaviness in the scrotum
  • pain in the testicle, scrotum, lower abdomen or back
  • breast tissue enlargement or tenderness.

If you notice lumps in one or both testicles, or changes in the shape of the testicle, visit your health care professional. They will conduct a physical examination and advise you on your next steps.

How is testicular cancer diagnosed?

Testicular cancer is diagnosed through a combination of:

  • examination - to check for abnormal lumps or shape
  • scans – ultrasounds and other scans to detect the presence of cancerous cells
  • blood tests – to look for certain proteins, called ‘tumour markers’, that are released by testicular cancer cells
  • surgery – to remove the testicle, if the scans and blood tests suggest testicular cancer, to check for cancerous cells.

Importantly, testicular cancer can’t be diagnosed through a biopsy (taking a small sample to check for cancerous cells). Cutting into a testicle may risk spreading the cancer to other areas of the body.

In Australia, routine screening is not recommended for testicular cancer. However, if you have a known family history or genetic mutation, talk to your health care professional about yearly screening.

How is testicular cancer treated?

Treatment depends largely on the stage of the cancer. If you have testicular cancer, your medical team will determine the stage of the cancer and whether it has spread. To do this, you may need to have additional tests, such as a chest X-ray and CT scans of the chest, abdomen and pelvis.

The different stages of testicular cancer are:

  • stage 1 – the cancer is only in the testicle
  • stage 2 – the cancer has spread to lymph nodes in the abdomen or pelvis
  • stage 3 – the cancer has spread to nearby organs.

The main treatment for stage 1 testicular cancer is to remove the testicle. This surgery is called an orchidectomy. If the cancer has spread to nearby organs, or certain features are seen within your tumour on microscopic examinations, other possible treatments include:

  • chemotherapy – treatment with drugs that kill cancer cells or slow their growth, often recommended after an orchidectomy
  • radiation therapy – a program of radiation therapy to destroy any remaining cancer cells.

Stage 2 or 3 cancer is generally still managed with removal of the testicle to identify the type of tumour and guide specific therapy, but most cases are then managed with systemic chemotherapy. Following this, if there are residual masses, surgery or radiation may be appropriate.

Your cancer specialist can discuss the options in detail to determine the best treatment program for you.

What can you do if you have testicular cancer?

If you have received a testicular cancer diagnosis, your medical team will give you a personalised treatment plan. It’s important to take the time to learn about your condition, treatments and future plan.

Connecting with other people who have cancer can help you to feel supported and not alone. A strong support network can be very beneficial for your emotional wellbeing, cancer management and treatment outcomes.

Your St Vincent’s cancer and men’s health teams will support you every step of the way.

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